The main active ingredients of Augmentin are two substances. First of all, it is a semi-synthetic antibiotic amoxicillin, belonging to the penicillin group, and clavulanic acid having a beta-lactam structure. Each component plays an important role in the mechanism of the pharmacological action of the drug.
Penicillin antibiotics have been known for a very long time. In fact, these were the first potent broad-spectrum antibacterial drugs invented by medicine. The principle of action of penicillins is based on the fact that they act on some enzymes contained in the cell wall of bacteria, and destroy it, so that bacteria die.
Augmentin, instructions for use
Augmentin should be taken only as prescribed by a doctor, self-medication with antibiotics is unacceptable, especially if the child is ill. The standard dosage of Augmentin in the form of tablets in the case of a light infection in adults is 250 + 125 g three times a day. In more severe cases, tablets of 500 + 125 g are prescribed three times a day. Or you can take 2 tablets Augmentin 875 + 125 g per day.
It should be borne in mind that Augmentin should be taken at strictly defined and equal time intervals. For example, if a drug is prescribed 3 times a day, then it should be taken every 8 hours. If you need to take pills 2 times a day, then this should be done every 12 hours. This technique allows you to maintain a constant concentration of the drug in the tissues of the body.
Augmentin is well tolerated by patients. Negative side effects when taking it are much less common than in the case of other antibiotics. However, they are not excluded.
Perhaps most often when taking the drug dysbacteriosis occurs. This is due to the fact that virtually any antibiotic (and Augmentin is not an exception to the rule) destroys not only pathogenic microorganisms, but also those that constitute its normal microflora, which lives primarily in the intestines, as well as on the skin and mucous membranes . As a result, patients undergoing antibiotic therapy can encounter such phenomena as mucosal candidiasis, candidal colpitis (in women), skin rash, diarrhea, and stomach pain.
Also, side effects associated with the nervous system (dizziness, headaches, anxiety, insomnia), allergic reactions (angioedema, anaphylactic shock, itching, urticaria), nausea, vomiting, dyspepsia, discoloration of the tooth enamel (while taking suspension) , kidney and liver damage (hepatitis). Liver dysfunction occurs most often in older men, as well as in those who already have problems with this organ. Patients with kidney problems or receiving high doses of the drug may have seizures.
If skin allergies occur, antibiotic treatment should be stopped. Rarely, changes in the composition of the blood can occur – agranulocytosis, neutropenia, leukopenia, thrombocytosis, eosinophilia, as well as anemia. All changes of this type are reversible.
Augmentin does not cause drug dependence, does not affect the reaction rate.